Drug candidate SR9009 is a simple molecule that produces significant benefits (Photo: The Scripps Research Institute)

Drug candidate SR9009 is a simple molecule that produces significant benefits (Photo: The Scripps Research Institute)

A new drug known as SR9009 is being tested on mice and the results so far are amazing. When given the drug the mice are not allowed to exercise. Even without exercise the mice become lean, build new, larger muscles and become capable of running 50% further than they could before taking SR9009. The drug somehow successfully mimics aerobic exercise.

The drug was developed by Professor Thomas Burris of TSRI, who found that it was able to reduce obesity in populations of mice. It binds to and activates a protein called Rev-ErbAα, which influences fat and sugar burning in the liver, production of fat cells, and the body’s inflammatory response.

Previous studies on mice lacking Rev-ErbAα showed decreased skeletal muscles, metabolic rate, and running capacity. Such mice appeared fated by their genetics to live as couch potatoes.

When Burris’ group administered SR9009 to these mice to activate the Rev-Erbα protein, the results were remarkable. The metabolic rate in the skeletal muscles of the mice increased significantly. The treated mice were not allowed to exercise, but despite this they developed the ability to run about 50 percent further before being stopped by exhaustion.

“We do have indications that the effects of the drug are very similar to what you see with someone who has metabolic disorder who starts exercising,” Burris stated in a Voice Of America interview. “They see a decrease in cholesterol, a decrease in triglycerides, an improvement in glucose metabolism. And a lot of this is due to transforming the muscle into a more metabolically active muscle.”

Man, all those people that have been busting their ass at the gym are going to be pissed when all those former fatties start gawking outside the gym window, pointing and laughing while drinking their Big Gulp, eating their Quarter Pounder and looking ripped as fuck.

Now, to find out how the hell I get in on those clinical trials!

H/T gizmag

Posted by James Poling

A socialist, tinkerer, thinker, question asker and all around curiosity seeker. If you'd like to reach me you can use the contact link above or email me at jamespoling [at] gmail [dot] com.

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